The aim of this study was to assess the medicinal properties, biological activities, and phytochemical components of Tridax procumbens, a plant species from the Asteraceae family with origins in Central and South America. A comprehensive review of the scientific literature was conducted using various databases such as Metadatabase EDS, MedLine (PubMed), Science Direct, Web of Science, Academic Search Premier, Scielo, DOAJ Directory of Open Access Journals, JSTOR, and others. A total of 130 studies were identified, out of which 111 were deemed relevant for this review. The findings underscore the need for further research to fully comprehend the potential therapeutic benefits of T. procumbens' secondary metabolites. This review highlights the significance of T. procumbens as an ethnobotanical resource with promising medicinal applications, particularly in tropical regions where it is indigenous and widespread.